Harvard Medicine home webweekly
March 24, 2008

In Print

Lewis Cantley (front), Matthew Vander Heiden, Heather Christofk
Liza Green, HMS Media Services

Substitute Protein in Energy Pathway Stalls Cancer Growth
Cancer cells may switch to a glucose-dependent route to satisfy their energy needs, a phenomenon first observed nearly 80 years ago by Otto Warburg. It now appears that they do so by reverting to the embryonic form of a key protein, pyruvate kinase, in the glycolytic pathway. Lewis Cantley (front), Matthew Vander Heiden, Heather Christofk, and colleagues found that they could turn off glycolysis in cancer cell lines by replacing the embryonic version of the protein with the adult form.

Upcoming

Public Health Intersections with Politics and the Harvard Center for Society and Health

Unnatural Causes: Is Inequality Making Us Sick?

Thursday, April 3
8:30 p.m.

Speakers:
•Nancy Krieger

Science Progress

How discovery happens.

 

Lab Works

A multimedia site featuring Harvard Medical research.

 




 

 

 

 

Spotlight

Match Day festivities
Liza Green, HMS Media Services

Match Day 2008
Medical students and their families gathered to celebrate the news of where the new MDs will serve as residents.

Student Scene

Joseph Ladapo
Graham Ramsay

The State’s Universal Health Care Program Needs TLC Itself
Joseph Ladapo diagnoses some of the ills of the Massachusetts health insurance program, maintaining that, with skilled treatment, it can recover.

StudenTalk

Personal takes on issues inside and outside the classroom.

 

 


Headlines

News from HMS and Its Affiliates

Simple Non-lab Methods as Good as Lab Tests at Predicting Cardiovascular Disease Risk

Scans Spot Hidden Tumors in Rare Cancer Syndrome

Joslin Researchers Discover New Effect for Insulin

Brain's Blood Supply Guides its Own Development

Study Verifies that Cholesterol-associated Gene Variants Can Predict Cardiovascular Events

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