In Print
Photo by Steve Gilbert/Photo Courtesy of Dimitri Krainc
From Focus:
Energy-boosting
Protein May Ease Neural Oxidative Stress
A molecule better known for turbo-charging muscles and burning fat may protect
brains from neurodegeneration, according to two independent studies of mice by
HMS researchers. The molecule, PGC-1 alpha, revs up mitochondria, the on-demand
cellular energy system. It also turns up enzymes to clean up the toxic emissions
of these cellular power plants, report Bruce Spiegelman (left) and his colleagues.
Further, PGC-1 alpha can worsen or protect brains in mouse models of Huntington’s
disease. The mutant huntingtin gene appears to attach to the DNA upstream of
the PGC-1 alpha gene and directly interfere with transcription, according to
researchers in the lab of Dmitri Krainc (right).
Upcoming
Program on the Global Demography of Aging
The Age Dynamics of Voting
Monday, November 13
4:30—6 p.m.
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Spotlight

Photo by Steve Gilbert
Scholars
in Medicine Marks 11th Year of Growth
The Eleanor and Miles Shore 50th Anniversary Fellowship Program
for Scholars in Medicine awarded 69 fellowships in a ceremony
last month. That's 14 more than last year. Kenneth Hancock (above
with family) was among the 2006 winners. Follow the link for
a complete list of recipients.
Student Scene
Pursuing Discovery in Medicine
Part of the new, integrated curriculum at HMS is a course on the role
of medical research. Developed by Terry Maratos-Flier and Ellen Seely,
the coursework will expose students to the step-by-step process of
scientific investigation. The class begins in January.
Lab Works
A multimedia site featuring Harvard
Medical research.
StudenTalk
Personal takes on issues inside and
outside the classroom.
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