In Print
Photo by Graham Ramsay From Focus:
Enzymes
Display Intricacy in Repackaging DNA
For almost a half century, methylation of DNA-binding histones was thought to
be irreversible. Two years ago, Yang Shi and colleagues discovered an enzyme
that could remove a methyl group from histones bearing two such groups. Now,
Johnathan Whetstine, Shi, Monica Colaiacovo (right to left), and colleagues report
that they have uncovered a whole family of enzymes that are capable of stripping
methyl groups not from dimethylated, but from trimethylated histones. Histone
modifications like these are increasingly seen as playing a role in cancer and
other diseases.
Upcoming
HMS/HSDM 10th Annual Mentoring Awards
Ceremony and Keynote Address
May 25
4:00–6:00 p.m.
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David Thomas
Harvard University Graduate School of Business
Lab Works
A multimedia site featuring Harvard
Medical research. |
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Spotlight

Photo by Leah Gourley
Critical Examination of Ethical Issues
This third vignette in a series on Medical Education Reform presents
Dan Brock’s perspective on Medical Ethics and Professionalism,
a new mandatory course for the first semester of the first year.
Brock heads the planning for the new course.
Student Scene

Photo by Steve Gilbert
The 66th Annual Soma Weiss Student Research
Day
In her investigation of polycystic ovarian sydrome, Meagan Murphy (above) found
good news for women concerned about developing the condition, which can cause
infertility. She was one of four student presenters on the program with keynote
speaker Eugene Braunwald.
StudenTalk
Personal takes on issues inside and
outside the classroom.
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