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Ever since the protein Sir2 was shown to make yeast live longer, scientists have been eager to study Sir2’s counterparts in mammals. Mammals have seven genes that are homologues to Sir2, called sirtuins, and only one has been studied in detail. Now a study led by the lab of Frederick Alt offers the first description of how a second member of the sirtuin family, SIRT6, functions in the body. Alt’s team shows that SIRT6 seems to play a role in repairing DNA damage, and mice that lack the gene display signs of premature aging.
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Photo
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Personal takes on issues inside and outside the classroom.
A multimedia site featuring Harvard Medical research.
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Image courtesy www.thefreddies.com
‘FREDDIE’ Honors
DFCI Video
An audiovisual program to explain cancer clinical
trials to patients, which was produced by the Dana–Farber Cancer Institute,
won an International Health and Medical Media “FREDDIE” Award
in the area of Issues and Ethics. Titled “Entering a Clinical Trial:
Is It Right for You?”, the video can be viewed at the above link.

The Second Year Show: “A Funny
Thing Happened on the Way to the Fornix”
In her review, Tarayn Grizzard tells why to be afraid of Andy-bodies
and—yikes!—four-color
pens. Photos by Steve Gilbert help tell the story.
Aaron Thurman Lecture on Humanism in Medicine
Preparing for Avian Flu: Lessons from the
Swine Flu Affair
Feb. 9
8:00 a.m.–9:00 p.m.
News from HMS and Its Affiliates
Timing of Hormone Therapy May Influence Coronary Risk
Study Using New Imaging Technology Detects Subtle Brain Changes in Patients with Type 1 Diabetes
Study Finds Nerve Damage in Previously Mysterious Chronic Pain Syndrome
Stopping Antidepressants During Pregnancy May Lead to Symptom Recurrence
Copyright 2006 by the President and Fellows of Harvard College