In Print
Photo by Graham Ramsay
From Focus:
Transcription
Apparatus Seen to Uncoil—and Recoil—DNA
Over the years, seminal contributions from the labs of Fred Winston (front),
Kevin Struhl (back), and Stephen Buratowski (left) have substantially changed
the understanding of DNA transcription, revealing how the transcriptional machinery
plays a role in not only unwinding but rewinding DNA. A recent paper by Struhl
and postdoctoral fellow Amita Joshi and another by Buratowski, his postdoc Michael
Keogh (right), and colleagues show how molecular modifications associated with
unwrapping DNA play a key role in repackaging it, thereby protecting it from
being transcribed inappropriately.
Upcoming
The Second Year Show:
A Funny Thing Happened on the Way to the
Fornix
Jan. 26–Jan. 28
7:00-10:00 pm
Lab Works
A multimedia site featuring Harvard
Medical research.
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Spotlight

Photo by Jeff Cleary
From Narratives to Networks: Annotation Mining Reveals Links Between Genes,
Biological Context
Isaac Kohane (above) and Atul Butte have linked biological concepts to gene
expression data in a new bioinformatics tool. The purpose is to enrich and,
perhaps, reconfigure the knowledge of gene networks in health and disease.
Student Scene

Photo by Jeff Cleary
O Canada!
Doc-to-be Tarayn Grizzard casts an envious eye on Canada’s health care
system. Despite its drawbacks, she says, this national organization serves the
bulk of care needs better than the U.S. system does. Is it time to relocate?
she wonders.
StudenTalk
Personal takes on issues inside and
outside the classroom.
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