In Print
Photo by Graham Ramsay From Focus:
Special
Delivery Brings Fats to Immune System
Proteins access the immune system by well-known pathways of antigen presentation,
but work by Michael Brenner and colleagues reveals that fat-containing antigens,
including those from pathogens like the TB bacterium, take a different and unexpected
route. They show that the immune system coopts apolipoproteins, best known as
blood cholesterol carriers, to obtain lipid antigens for presentation to T cells.
The convergence of two previously unrelated systems—the transfer of dietary
fats and cholesterol and the delivery of lipid antigens to the immune system—has
profound implications for understanding a host of diseases from atherosclerosis
to asthma.
Upcoming
30th Annual Joseph Garland Lecture:
How Science, FDA, and Industry Shape Our Prescribing Decisions
Wednesday, Oct. 26
5:30–6:30p.m.
- Jerry Avorn
Brigham and Women’s Hospital
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Spotlight
An
Interactive Intro to Proteomics
Children’s Hospital Boston now features a website giving the ABCs of
proteomics, discussing the key technologies of 2-D electrophoresis, mass
spectroscopy, and informatics.
Student Scene
Photo by John Rich
HST Celebrates 35-year
Milestone
The Harvard–MIT Division of Health Sciences and Technology celebrated
its 35th anniversary in September. Events included a poster session and talks
by 16 HST alums, including Barbara Smith, an ’83 grad and HMS assistant
professor of surgery at Massachusetts General Hospital.
Lab Works
A multimedia site featuring Harvard Medical research.
StudenTalk
Personal takes on issues inside and outside the classroom.
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