In Print
Photo by Graham Ramsay
From Focus:
Alzheimer's Plaques Reversed in Mice by Blocking Cholesterol Pathway
It has been almost 100 years since Alois Alzheimer described the senile plaques characterizing the disease that now bears his name. Since then, researchers have been trying to figure out how to prevent the build-up of those plaques and the associated neurodegeneration. In a recent study, Dora Kovacs (above), Henri Huttunen, and colleagues describe a novel approach that works remarkably well in young mice with Alzheimer's-like pathology. By inhibiting an enzyme that redistributes cholesterol in the cell, they have reduced the plaques by up to 99 percent and improved learning and memory in the most afflicted animals.
Upcoming
Eighth Annual National Center for AIDS Research Symposium
"HIV 2004: From Basic Science to Global Treatment Implementation"
Nov. 11, 2004
NRB
Windows on a Hidden World: Disease Modeling Symposium
Nov. 17, 2004
NRB
Lab Works
A multimedia site featuring Harvard Medical research.
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Spotlight
Open-Access Journal for Neuroengineering Debuts on Web
The new open-access Journal of NeuroEngineering and Rehabilitation has begun publication online and is seeking manuscripts on research blending neuroscience, biomedical engineering, and physical medicine and rehabilitation. Editor-in-chief Paolo Bonato is on the HMS faculty at Spaulding Rehabilitation Hospital.
Student Scene
Photo by Jeff Cleary
"Dr. Mom?"
Many of the patients that Tarayn Grizzard sees as a lactation counselor in Lima, Peru, ask why she doesn't have any children. She finds that her answer is not wholly satisfying, to her patients or to herself.
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