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August 11, 2003

In Print

Mary-Elizabeth Patti (left) and the other by David Altshuler
Photo by Steve Gilbert

From Focus:
Gene Players May Tip Balance to Diabetes

The number and activity of energy-producing mitochondria in muscle cells rise with exercise and fall in diabetes by unknown mechanisms. Two Harvard Medical School research teams, one headed by Mary-Elizabeth Patti (left) and the other by David Altshuler, have found a group of related genes that slack off in unison to slow down the mitochondria. This downregulation may tip the scales to insulin resistance, the first metabolic misstep on the road to diabetes.

 

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Spotlight

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Project Success Boasts 10 Years of Science Enrichment
Nineteen high school students from Boston and Cambridge are participating in this summer's Project Success, a lab research program of the HMS Office for Diversity and Community Partnership, which celebrates its 10th anniversary this year.

Lab Works

A multimedia site featuring Harvard Medical research

 
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