May 12, 2003
In Print Photo by Steve Gilbert Focus: A Mechanism Discovered for Antibody Deployment Antibodies dispersed by B lymphocytes learn where and how to fight pathogens by genetic changes known as class switch recombination. Two studies from Frederick Alt's lab show the first steps in a crucial enzyme's genetic modification of the switch region, which customizes the end of the antibody gene and determines how the antibody will mount its defense. When the mechanism goes awry, it may contribute to some cancers.   Publications Online BBS Bulletin Focus HMI World HSTconnector MD-PhD Newsletter MedEd News Mentations On The Brain   Related Links InteliHealth Harvard Health Publications		Headlines Medicare Patients in Managed Care Programs More Likely to Use Hospice Care Researchers Identify Important Function of NF2 Tumor Suppressor Upcoming AIDS Symposium: Harvard Programs on AIDS and Global Health: Drugs for Prevention and Treatment Several presenters Wednesday, May 14 8:00 a.m.-3:30 p.m. Lab Works A multimedia site featuring Harvard Medical research		Spotlight Seidman Speaker Sees Health Care Spending Likely to Keep Rising At the third annual Seidman lecture, Gail Wilensky (talking to Marshall Seidman above) described the easing of health care spending in the 1990s as an economic exception and the current rise as the rule. There's no indication the rule will change anytime soon, she said. Student Scene Photo by Graham Ramsay A Quandary in Caring for Alcoholic Patients Practicing in Arizona on the Navajo Reservation, Ellen Rothman frequently deals with alcoholic patients. Their patterns of alcohol abuse differ from those of patients at other sites where she has worked. Unfortunately, effective treatment is particularly elusive.

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