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March 17, 2003

In Print

Jonathan Seidman, Christine Seidman, and Joachim Schmitt
Photo by Graham Ramsay

Focus:
Mutation that Disrupts Calcium Signaling May Be One Cause of Heart Failure

A recent mouse study by Jonathan Seidman, Christine Seidman, and Joachim Schmitt (l to r) provides the first evidence that a loss of calcium signaling can cause congestive heart failure. The researchers found that a mutation in the protein phospholamban in cardiac muscle cells led to an inability to pump calcium back into appropriate cell reservoirs. The disruption led to contractile dysfunction of the heart.

 

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New Analysis Suggests Leading Sleep Apnea Treatment Is Effective in a Diverse Population

Adverse Drug Events Are Common in Older Patients

Upcoming

Ethics Forum:
Ethics and AIDS Vaccine Trials in the U.S. and Abroad

Marcia Angell, Harvard Medical School
George Seage III, Harvard School of Public Health
Daniel Wikler, Harvard School of Public Health
Tuesday, March 25
4:00-6:00 p.m.

Lab Works

A multimedia site featuring Harvard Medical research

 

Spotlight

herman taylor Jackson Study Confronts the Heart of an Epidemic
In the March 4 Barger lecture, Herman Taylor Jr., director and principal investigator of the Jackson Heart Study, said there is no adequate explanation of the cause in about a quarter of cardiovascular disease cases. He plans to change that through expanding the scope of potential risk factors that this study of African Americans investigates.

Student Scene

erica seiguer
Photo by Graham Ramsay
Campaign Gains Strength Against Overuse of Antibiotics
Bacteria are developing resistance to some of the most potent antibiotics available, decreasing the effectiveness of last-ditch medications. Erica Seiguer describes some of the U.S. efforts to limit the use of antibiotics, a strategy for turning the tables on the bugs.

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