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February 24, 2003

In Print

judy and premlata
Photo by Steve Gilbert

Focus:
RNA Interference Cuts Hepatitis Down to Size

For the first time in an animal model, researchers have shown the therapeutic punch of the gene-silencing technique RNA interference. This method of reducing gene expression took off five years ago when researchers discovered double-stranded RNA could stifle genes in the early stages of activation. Now, Judy Lieberman (left), Premlata Shankar, and colleagues report that small pieces of RNA can prevent liver injury and death in mice with chronic and severe autoimmune hepatitis.

 

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Elderly with Head and Neck Cancer May Benefit from More Aggressive Cancer Treatments

Rheumatoid Arthritis and Cardiovascular Disease May Be Linked in Women

New Drug Combination Improves Survival in Rare, Aggressive Bone Cancer of Children and Young Adults

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Spotlight

dancing student Second-years Put On Swell Show
The Second Year Show, "My Big, Fat Distal Swelling," cuts its own big, fat, new pathway through the medical education experience at Harvard.

Forum

Jan Schmollinger
Photo by Graham Ramsay
Physicians with Death Row Patients May Face Deadly Dilemma
An appeals court recently ruled that a psychotic death row inmate should receive antipsychotic medication because it would alleviate the risk he poses to himself and others. The decision has the unintended consequence of also making the prisoner sane enough to be legally executed. Jan Schmollinger argues that the ruling creates a special ethical dilemma for physicians who work in the penal system.

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