August 12/August 19, 2002
In Print Photo by Graham Ramsay Focus: Molecular Target Found for Boosting T Cell Tolerance Research by Anjana Rao and colleagues demonstrates that the transcription factor NFAT mediates two completely opposing immune responses. If the factor binds with molecular partner AP-1, it helps T cells respond to foreign antigens. If it does not, it induces a state of unresponsiveness in which the T cells tolerate antigens. The investigators are exploring how to take advantage of this mechanism to aid transplant patients in tolerating their new organs. BBS Bulletin HMI World HSTconnector InteliHealth MD-PhD Newsletter MedEd News Mentations On The Brain		Headlines How the Brain Keeps Extra Calories from Becoming Extra Pounds Researchers Identify Brain Pathway to Explain How Fenfluramine Causes Weight Loss Fat Tissue Can Be Controlled by the Blood Vessels that Feed It Study Shows Light Must Pass Through Eyes to Shift the Human Circadian Clock Researchers Find Potential New Use for Cholesterol-lowering Drugs Study Suggests Lack of Health Care Access to Blame for Lower Survival Rates for African-Americans with Colon Cancer Immune System Component Found Common to both Humans and Worms Time-release Stimulant Effective for Once-daily Treatment of ADHD McLean Researchers Uncover New Link Between Ritalin and Brain Upcoming Student Intern Presentations for 2002 of the Harvard Green Campus Initiative Thursday, August 29 3:00-5:00 p.m. Lab Works A multimedia site featuring Harvard Medical research		Spotlight Voice Disorders Website Speaks Volumes Massachusetts Eye and Ear Infirmary's Voice Disorders Center has established a website explaining its organization and the disorders it treats. The site will be of interest to both physicians and prospective patients. Above, Voice Disorders Center codirectors are Steven Zeitels (left) and Robert Hillman. Student Scene Photo by Jeff Cleary Tolerating the Uncertainty Principle Uncertainty is a natural part of clinical practice since few illnesses follow a totally predictable course from start to finish. Tarayn Grizzard believes that if managing uncertainty had a higher profile in medical education, students would suffer less anxiety about the clinical unknowns.

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