December 9, 2002
In Print Photo by Jeff Cleary Focus: Enzyme Implicated in Insulin Resistance A study by Gürol Tuncman, Gökhan Hotamisligil (l to r), and colleagues identifies an inflammatory mechanism in a mouse model that helps drive the development of obesity, insulin resistance, and type 2 diabetes. Central to their findings is the discovery of an enzyme in fat, muscle, and liver cells that appears crucial to the pathway for obesity-induced insulin resistance and, perhaps, obesity itself. BBS Bulletin HMI World HSTconnector InteliHealth MD-PhD Newsletter MedEd News Mentations On The Brain		Headlines Study Predicts Risk of Death from Prostate Cancer Bottle Feeding Before Bed Time May Increase Risk of Childhood Asthma Chlamydia Pneumoniae May Contribute to Heart Attacks and Strokes Upcoming History of Medicine Colloquium: Medical Ethics in the Shadow of the Holocaust: The Nazi Doctors, Racial Hygiene, Murder, and Genocide Michael Grodin, Boston University Thursday, December 19 4:00-5:30 p.m. Lab Works A multimedia site featuring Harvard Medical research		Spotlight Photo by Steve Gilbert HMS Lends Hand to Landmark Mouse Genome Study Researchers at HMS, particularly those at the Harvard-Partners Center for Genetics and Genomics, directed by Raju Kucherlapati, contributed to the recent major report on the mouse genome. The center cloned small portions of the genome with great detail and accuracy and added their findings to the larger effort. Forum Photo by Jeff Cleary Scientific Sloppiness is Bad News for Translational Research The scientific misconduct in the news recently in physics and other laboratories is especially threatening to research that brings findings from the bench to the bedside, says Jan Schmollinger. If the public loses trust in trial safeguards, regulations may increase and patient volunteers decline.

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