December 13, 1999

Protein May Turn Brain Enzyme into Trigger for Alzheimer's Tangles Li-Huei Tsai, Gentry Patrick (l to r), and colleagues have discovered a protein that kicks off the molecular chain of events leading to the tangles of Alzheimer's disease. In postmortem exams, these intertwined filaments clutter the insides of dead brain cells.

Harvard Affiliates Launch Cancer Collaborative to Accelerate Development of New Therapies Gene Therapy May Be Able to Reverse Heart Failure Weight Gain Shown to Negatively Affect Quality of Life MRI Found to Be Effective Follow-Up for Evaluation of Fetal Abnormalities

The Dean's Millennium Series The 1999 Dunham Lectures Grey Matter(s) December 15, 16, and 17

Seeing the Parents'-Eye View of a Broken Child As a second-year pediatric resident, Ellen Rothman has begun to understand the deep attachment some parents have for their severely impaired children.

Primary Care Residency Makes Case for Training Linked to Managed Care The American Board of Internal Medicine has recognized the Harvard Pilgrim Health Care/Brigham and Women's Hospital Primary Care Residency as one of the most innovative in the country. The director, Jeannette Shorey, was invited to give a presentation on the program and its financial challenges last August, and the board recently put her talk up on the Web.